Inflammatory Bowel Disease (IBD) is the collective condition label given to a number of gastrointestinal (GI) disorders that result in colitis of the GI tract, or chronic gut inflammation.
IBD is now considered an emerging global disease with increasing prevalence, severity and complexity especially in western societies.
The baseline treatment and avoidance of inflammatory events can be approached from a dietary perspective and studies demonstrate a role for prebiotics, probiotics and the synergistic combination administration, labelled synbiotics.
Kfibre is a unique prebiotic phytonutrient fibre extract from sugarcane, manufactured to preserve the cell wall components and phytonutrient bioactives providing a representative cellular fibre component from plant dietary sources.
These components target the normalisation of gut microbiota, the production of beneficial by-products of microbial digestion (such as short chain fatty acids) and the delivery of plant antioxidants to the colon. Kfibre delivers more antioxidant capacity than green tea.
Research Partner – University of Tasmania (UTAS) & University of Queensland
Health Food Symmetry‘s University research partner (UTAS) holds a provisional patent for the prophylaxis and treatment of Inflammatory Bowel Disease using sugarcane cellular complex (Kfibre), and KFSU Ltd has exclusive global rights for commercialisation.
Evidence supporting the patent comes from a scientific animal trial whereby Kfibre, as both a standalone treatment, and as a synbiotic (combination of Kfibre and a probiotic bacterial strain), significantly reduced or prevented gut inflammation (colitis).
Two models for anti-inflammatory effect have been used, DSS (a chemical trigger) and Winnie mouse model (a genetic variant that develops spontaneous colitis).
Use of both an environmental trigger and a genetic dysfunction provides the highest confidence that these results will be replicated in humans supporting the existing anecdotal evidence.
Both models resulted in significant reductions in inflammation on the Disease Activity Index (DAI). Pathology performed on the subjects also demonstrated large reductions in inflammation as measured by C-Reactive Protein (CRP) biomarkers. These inflammation marker reductions were also noted from the pathology performed during the 90 person Kfibre weight loss study.
The full paper to the published results in the journal “Nutrients” can be found at the following link:
- Synbiotic Supplementation Containing Whole Plant Sugar Cane Fibre and Probiotic Spores Potentiates Protective Synergistic Effects in Mouse Model of IBD o Nutrients 2019, 11, 818; doi:10.3390/nu11040818